Editorial: Auditory Efferent System: New Insights from Cortex to Cochlea
نویسندگان
چکیده
1 Programa de Fisiología y Biofísica, Instituto de Ciencias Biomédicas (ICBM), Facultad de Medicina, Universidad de Chile, Santiago, Chile, 2 Departamento de Otorrinolaringología, Hospital Clínico de la Universidad de Chile, Santiago, Chile, 3 Facultad de Medicina, Instituto de Investigaciones en Ingeniería Genética y Biología Molecular, Dr. Héctor N. Torres (INGEBI), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET) Buenos Aires, Argentina, 4 Tercera Cátedra
منابع مشابه
Corticofugal modulation of peripheral auditory responses
The auditory efferent system originates in the auditory cortex and projects to the medial geniculate body (MGB), inferior colliculus (IC), cochlear nucleus (CN) and superior olivary complex (SOC) reaching the cochlea through olivocochlear (OC) fibers. This unique neuronal network is organized in several afferent-efferent feedback loops including: the (i) colliculo-thalamic-cortico-collicular; (...
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Objectives: Otoacoustic emissions (OAEs) are sounds that originate in cochlea and are measured in external auditory canal and provide a simple, efficient and non-invasive objective indicator of healthy cochlear function. Olivo cochlear bundle (OCB) or auditory efferent system is a neural feedback pathway which originated from brain stem and terminated in the inner ear and can be evaluated non-i...
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BACKGROUND The auditory efferent system has unique neuroanatomical pathways that connect the cerebral cortex with sensory receptor cells. Pyramidal neurons located in layers V and VI of the primary auditory cortex constitute descending projections to the thalamus, inferior colliculus, and even directly to the superior olivary complex and to the cochlear nucleus. Efferent pathways are connected ...
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Electromotile activity in auditory outer hair cells (OHCs) is essential for sound amplification. It relies on the highly specialized membrane motor protein prestin, and its interactions with the cytoskeleton. It is believed that the expression of prestin and related molecules involved in OHC electromotility may be dynamically regulated by signals from the acoustic environment. However little is...
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Efferent innervation of the cochlea undergoes extensive modification early in development, but it is unclear if efferent synapses are modified by age, hearing loss, or both. Structural alterations in the cochlea affecting information transfer from the auditory periphery to the brain may contribute to age-related hearing deficits. We investigated changes to efferent innervation in the vicinity o...
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